Tottenham Hotspur take on Internazionale in what is arguably the biggest game of their season so far.
Spurs are third in their Champions League group and need all three points if they are to give themselves a chance of progressing.
They currently have four points, with Inter in second on seven.
Barcelona are effectively already through, meaning only one of Tottenham or Inter can qualify with them.
Mauricio Pochettino needs big performances all over the pitch on Wednesday, and one man who could tip the balance is a rejuvenated Heung-min Son.
Son impressed against Chelsea at the weekend, scoring a fantastic solo effort which will surely contest the next Premier League Goal of the Month competition.
Son vs D’Ambrosio
With Son likely to feature on the left, it’ll mean he comes up against Danilo D’Ambrosio.
The Italian has been a regular in the side under Luciano Spalletti this season, with loan star Sime Vrsaljko having struggled with injury.
The 30-year-old has done fairly well to his credit whilst filling in for the Croatian, but he faces a tough test in the form of Son at Wembley.
The South Korean seemed jaded earlier on in the season after the World Cup and the Asian Games, but he appears to be coming back into form and fitness now.
His display against Chelsea was a reminder of how dangerous he can be.
D’Ambrosio does struggle to deal with pace more than anything, and Son could really wreak havoc against him.