Southampton missed out on a quarter-final spot in the EFL Cup when they were beaten on penalties by Leicester City.
It was an improved performance from struggling Southampton but after the game ended in a 0-0 draw, Leicester edged it on penalties.
Manolo Gabbiadini missed the decisive penalty for the Saints.
And given the fact that he is out of favour at Southampton, this could spell the end of his career on the south coast.
With the January transfer window now just one month away, Gabbiadini might seek an exit in the new year to resurrect his career elsewhere.
The Italian striker has struggled with his form for a while now after an impressive start to life at Southampton.
This season, he has one goal in 12 outings and he only managed five goals in 33 games last term.
It could have been different for the 27-year-old last night as he hit the woodwork on extra time, but it ended on a sour note.
Gabbiadini saw his spot kick saved by Danny Ward and that ultimately cost Southampton a place in the quarter-finals.
With Danny Ings and Charlie Austin preferred to him, and now Michael Obafemi sneaking ahead of him in the pecking order, it is time for Gabbiadini to pursue his career elsewhere.